Mielinolisis central pontina pdf download

Cartas al director mielinolisis central pontina tras sindrome neuroleptico maligno sr. A diagnosis of central pontine myelinolysis cpm was made. It is predominately iatrogenic treatmentinduced, and is characterized by acute paralysis, dysphagia difficulty swallowing, dysarthria difficulty speaking, and other neurological symptoms. Central pontine myelinolysis cpm is a neurological condition involving severe damage to the myelin sheath of nerve cells in the pons an area of the brainstem. As such the condition is described in the osmotic demyelination syndrome article. Central pontine myelinolysis has been well known for more than 40 years and mainly occurs in alcoholics. Extrapontine myelinolysis is an acute unusual process, included in demyelinating syndromes of metabolic etiology, which differentiate from central pontine myelinolysis, by affecting other brain areas with clinical manifestation such as dystonia, catatonia, postural tremor, myoclonic spasm, parkinsonism or pyramidal sings.

Mielinolisis central pontina en trasplante hepatico medicina intensiva. Central pontine myelinolysis cpm and extrapontine myelinolysis epm are rare neurological disorders characterized by demyelination in andor outside the pons. This condition, however, has also been found in the malnourished, transplant recipients, or chronically debilitated patients,in particular, those in whom electrolyte. Pontine and extrapontine myelinolysis are usually due to a rapid correction of hyponatraemia. Role of neuroimaging in the diagnostic evaluation of central. Several cases of hyperglycaemia and ketoacidosis associated with alterations in sodium levels 1,4 have been reported in recent years, suggesting that hyperglycaemia associated with hyponatraemia should be added to the list of risk factors alcoholism, malnutrition, etc. Central pontine myelinolysis cpm is now more commonly referred to as osmotic demyelination syndrome, which recognizes that the same phenomenon is also seen in other areas of the brain previously known as extrapontine myelinolysis. Pdf mielinolisis pontina central e hiponatremia perioperatoria.

Perspectives on critical care infectious diseases, vol 1. We use your linkedin profile and activity data to personalize ads and to show you more relevant ads. A magnetic resonance imaging showed a central and symmetrical pontine lesion on t1 and t2 weighed images. Osmotic demyelination syndromes include pontine and extrapontine myeli nolysis. The original patient population included only chronic alcoholics. Central pontine myelinolysis cpm is the most severe neurological complication after liver transplantation and apparently is not. Mielinolisis, desmielinizacion, hiponatremia, paralisis pseudobulbar, osmolaridad. This condition, however, has also been found in the malnourished, transplant recipients, or chronically debilitated patients,in. Central pontine myelinolysis after liver transplantation. Value of diffusionweighted imaging in central pontine and. A mielinolise pontina central mpc e uma doenca desmielinizante aguda causada por oscilacoes abruptas na osmolalidade serica, resultando em desmielinizacao simetrica da parte central da base da ponte. Pdf mielinolisis central pontina en trasplante hepatico. Mielinolisis central pontina en trasplante hepatico.

Pdf central pontine myelinolysis is a demyelinating lesion in the basis pontis which in most cases is caused by a rapid correction of hyponatremia. Mielinolisis pontina central e hiponatremia perioperatoria. Role of neuroimaging in the diagnostic evaluation of. Enfermedades desmielinizantes del sistema nervioso central. Citescore values are based on citation counts in a given year e. Mielinolisis central pontina en trasplante hepatico central pontine myelinolysis in a.

Brain mri of the patient showing a low t1 signal intensity lesion day 14. Pontine and extrapontine myelinolysis secondary to. Ocorre esporadicamente em todas as idades 35, acomete os dois sexos igualmente e sua incidencia exata e desconhecida 4. T2 weighted image of hyperintensity in the pons black arrow consistent with cpm day 14. At the 4th day of admission, the patient was again stuporous and with spastic quadriplegia. We report a 69 years old woman with a history of one month of vertigo, nausea, vomiting and diarrhea. Central pontine myelinolysis cpm was first termed in 1959 by adams to describe a symmetric, demyelinating focus prominent in the central pons. It is characterized by demyelinization of the white matter. Whether diffusionweighted imaging dwi might facilitate an earlier diagnosis has not yet been studied systematically. Mielinolisis central pontina tras sindrome neuroleptico. Serum sodium raised to 120 meql at the next day and the level of consciousness improved. Convulsiones, estado mental alterado mielinolisis pontina central 82. Pontine and extrapontine myelinolysis secondary to glycemic.

Magnetic resonance imaging showed demyelination of the motor pathway only in the protuberance. Chronic alcoholism or rapid correction of hyponatremia was present in over 75% of cases. Central pontine myelinolysis cpm is the most severe neurologi. Saner fh, koeppen s, meyer m, kohnle m, hergetrosenthal s, sotiropoulos gc, et al. Antemortem computed tomography ct had been performed in nine, and ante or postmortem magnetic resonance mr imaging in 11. We describe demographics, clinical presentation, and early magnetic resonance imaging mri findings with special. Files are available under licenses specified on their description page.

Mielinolisis central pontina en trasplante hepatico core. Scribd is the worlds largest social reading and publishing site. Role of neuroimaging in the diagnostic evaluation of central nervous system lesions and infections in organ transplant recipients. Mielinolisis central pontina tras sindrome neuroleptico maligno sr. Mielinolisis extrapontina secundaria a hiponatremia por. All structured data from the file and property namespaces is available under the creative commons cc0 license. Central pontine myelinolysis radiology reference article. Aug 30, 2012 central pontine myelinolysis cpm and extrapontine myelinolysis epm are rare neurological disorders characterized by demyelination in andor outside the pons. Mielinolisis central pontina en trasplante hepatico central pontine myelinolysis in a liver transplant recipient. Treatment of central pontine myelinolysis with plasmapheresis and immunoglobulins in liver transplant patient.